Let's look at the second database: Embase
There are several ways to get to Embase from the HSL website. The easiest is probably to select the Embase link on the first page of the pharmacy guide. This link will take you to the quick search page, where you can type in your initial search terms. When you start a search in Embase, Embase defaults to its "search as broadly as possible" option, which will automatically map your search to any applicable Emtree terms if they exist. For example, if you type in type 2 diabetes, you'll see that Embase suggests using the Emtree term non-insulin dependent diabetes mellitus. Unlike with PubMed you will want to go ahead and put the terms that Embase suggests as Emtree terms into quotes.
Embase will search as broadly as possible for your first search, for all subsequent searches this box will be unchecked. Make sure you recheck it before each search.
Why do we use quotes with Embase and not with PubMed?
In PubMed, using quotes turns off the mapping to MeSH so you don't want to use quotes when starting a search. However, Embase will only search for Emtree terms one word at a time, so in order for Embase to find the full entry term you'll need to put quotes around the whole phrase.
Embase makes it easy to find Emtree terms with its auto-suggest feature; however, it is a good idea to check out the Emtree database, as this will give you additional information about each term. To get to the Emtree database from the search page, select Emtree at the top of the Embase search page.
If you search for type 2 diabetes here, it will once again suggest non-insulin-dependent diabetes mellitus. If you click on this term, it will take you to the Emtree entry for this term, which will show you where the term is in the tree as well as the history of the term, synonyms for the term, and some dictionary definitions for the term. The synonyms in Emtree tend to be a little bit more robust than the synonyms in MeSH so it's a good idea to take a look at the list when you're looking for synonyms.
In addition to using the auto suggestion to find Emtree terms, you can also find Emtree terms from published articles, the same way you did in PubMed. Once you've completed a search, you can click on a study that is of interest to you, look at its Emtree terms, and then add any terms of interest to your search.
One of Embase’s other interesting features is its drug search.
To use Embase's drug search-specific headings, select "drug" from the search menu on the left. Here you can enter either a drug name or a drug class (e.g., linagliptin or dipeptidyl peptidase-4 inhibitor). You also have the option to add things like drug field, where you can search for a drug manufacturer or trade name, drug subheadings (something like an adverse drug reaction or pharmacokinetics), or the route of administration.
For example, you can search for adverse drug reactions to metformin administered orally.
Embase also makes it easy to combine searches. Once you have several terms or strings of terms on each line, you can use AND, OR, or NOT to combine your searches.
For example, if you wanted to search for diabetes treated with dpp-4 inhibitors or metformin in the search below, you could search for #2 AND (#3 OR #4).
Embase also contains search filters similar to the ones in PubMed. These filters are found along the left-hand side of your search results page and include options that you can also find in PubMed, like:
Embase also contains additional filters that you cannot find in PubMed. These allow you to narrow your search to a specific drug, disease, device, or specific subheadings.
To sum up Emtree searching, there are three ways to look for Emtree terms:
A few final Embase tips: