In addition to searching for research similar to your own, you will need to look for literature that mentions alternatives involving reduction, refinement, and replacement of animals in laboratory research. There are a lot of keywords that you can use to perform these searches, many of which are listed below.
Sample Animal Alternatives MeSH Keywords & Searches for PubMed MEDLINE
When searching PubMed or one of the other MEDLINE interfaces, it is often a good idea to use the Medical Subject Headings (MeSH) to find relevant articles. MeSH headings are assigned to each article within MEDLINE by its staff and are intended to be consistent across articles. This allows them to return more relevant and consistent groups of articles when searched.
PubMed provides a searchable MeSH Database to help you identify the best terms for your search, which includes many that apply to a literature search for alternative research methods in animal studies.
If you use a MeSH term, you must tell PubMed that you want it to be a MeSH term and not something else in order to find the most relevant results. To do this, type the term inside quotation marks followed by [MESH]. See below for examples.
Sample standard MeSH keywords (click on the keyword to see the MeSH definition, if available):
MeSH terms can be combined to produce generalized searches for major topics in animal testing, including the health, welfare, and housing of animal subjects. Listed below are some sample searches for major issues of interest in your literature search.