Once you have found systematic reviews or clinical research articles related to your question you must critically evaluate the research and how it is reported. Even a Cochrane systematic review should be read critically!
Critical appraisal is the process of reading research papers with an focus on:
examining whether the results are valid and unbiased;
understanding and evaluating the report of the results;
deciding whether these results can be applied to your patient(s).
Critical Appraisal Worksheets
Appraisal tools can guide you through the process of critically reading an article.
This detailed, yet highly readable reference demystifies the statistical, analytical, and clinical principles of evidence-based medicine, giving you a hands-on, practical resource that no other text can match. Here, you'll learn how to distinguish solid medical evidence from poor medical evidence, devise the best search strategies for each clinical question, critically appraise the medical literature, and optimally tailor evidence-based medicine for each patient.