COVID-19 (Coronavirus) Resources

In order to ensure immediate access to Cochrane Reviews of potential relevance, this Cochrane Library Special Collection assembles Cochrane Reviews identified as most directly relevant to the prevention of infection. It includes reviews that evaluate the effects of interventions referenced in the WHO interim guidance for the 2019 coronavirus outbreak (28 January 2020), as well as other potentially relevant reviews from three Cochrane Networks.

Please note that the reviews included in this Special Collection summarize evidence, and their inclusion does not mean that the interventions reviewed have been shown to be an effective prevention measure.

This Special Collection includes Cochrane Reviews on the following topics: fluid and vasopressor therapy; respiratory support and mechanical ventilation; weaning mechanical ventilation; managing hypoxaemia; pharmacological treatment; and nutrition in intensive care. Many reviews in the collection have associated Cochrane Clinical Answers, with links provided.

It is important to note that the reviews included in this Collection summarise evidence; their inclusion does not mean that they are an effective treatment. A number of reviews presented here highlight the paucity of high-quality evidence to inform medical decision-making in the context of the severe acute respiratory infection (SARI) crisis.

Health care providers in consultation with the state Communicable Disease Branch (919-733-3419, available 24/7) or local public health department will conduct a risk assessment to determine if individuals meet the NC criteria for diagnostic testing to detect COVID-19. When the criteria are met, a NC Patient Under Investigation (PUI) number is assigned, documenting approval for testing. Prior approval from the Communicable Disease Branch is required for submission of specimens.

Health care providers in consultation with the state Communicable Disease Branch (919-733-3419, available 24/7) or local public health department will conduct a risk assessment to determine if individuals meet the NC criteria for diagnostic testing to detect COVID-19. When the criteria are met, a NC Patient Under Investigation (PUI) number is assigned, documenting approval for testing. Prior approval from the Communicable Disease Branch is required for submission of specimens.

Health care providers or public health personnel collecting specimens should wear recommended PPE as described in this document.

Clinicians will learn what they can do to prepare for COVID-19 including identifying persons under investigation, applying infection prevention and control measures, assessing risks for exposures, optimizing the use of personal protective equipment supplies, and managing and caring for patients (inpatient and at home).

Infection control procedures including administrative rules and engineering controls, environmental hygiene, correct work practices, and appropriate use of personal protective equipment (PPE) are all necessary to prevent infections from spreading during healthcare delivery. Prompt detection and effective triage and isolation of potentially infectious patients are essential to prevent unnecessary exposures among patients, healthcare personnel, and visitors at the facility. All healthcare facilities must ensure that their personnel are correctly trained and capable of implementing infection control procedures; individual healthcare personnel should ensure they understand and can adhere to infection control requirements.

COVID-19 Fact Sheets available in 34 languages. All materials are reviewed and vetted by physicians and medical school faculty members at the Harvard hospitals, created in collaboration with Harvard Health Publishing.

The NC Department of Health and Human Services issued a temporary order requiring clinicians to report suspected or confirmed cases of 2019 novel coronavirus (2019-nCoV) to the local health director in their county or district. Read the Feb. 3 temporary order

NCDHHS also released updated clinical guidance to provide NC clinicians with the latest information on the illness. Read the Feb. 3 guidance.

Digital Science is providing all relevant content on COVID-19 in Dimensions as a single export file, updated daily, to make sharing and distributing this research information easier.
Access the Google Sheet
Access the CSV file on Figshare

It includes a clean, ready-to-use data stream of case reports, compiled by Johns Hopkins University and including data from WHO and the CDC; a jumpstart workbook; and a curated gallery of the best visualizations created by Tableau users.

Resources include guidelines, reports, proceedings, trainings, fact sheets, etc., for a professional audience.

In order to ensure immediate access to Cochrane Reviews of potential relevance, this Cochrane Library Special Collection assembles Cochrane Reviews identified as most directly relevant to the prevention of infection. It includes reviews that evaluate the effects of interventions referenced in the WHO interim guidance for the 2019 coronavirus outbreak (28 January 2020), as well as other potentially relevant reviews from three Cochrane Networks.

Please note that the reviews included in this Special Collection summarize evidence, and their inclusion does not mean that the interventions reviewed have been shown to be an effective prevention measure.

This Special Collection includes Cochrane Reviews on the following topics: fluid and vasopressor therapy; respiratory support and mechanical ventilation; weaning mechanical ventilation; managing hypoxaemia; pharmacological treatment; and nutrition in intensive care. Many reviews in the collection have associated Cochrane Clinical Answers, with links provided.

It is important to note that the reviews included in this Collection summarise evidence; their inclusion does not mean that they are an effective treatment. A number of reviews presented here highlight the paucity of high-quality evidence to inform medical decision-making in the context of the severe acute respiratory infection (SARI) crisis.

LitCovid is a curated literature hub for tracking up-to-date scientific information about the 2019 novel Coronavirus. It is the most comprehensive resource on the subject, providing a central access to 737 (and growing) peer-review articles. The articles are updated daily and are further categorized by different research topics and geographic locations for improved access.

In response to the COVID-19 pandemic, the Allen Institute for AI has partnered with leading research groups to prepare and distribute the COVID-19 Open Research Dataset (CORD-19), a free resource of over 29,000 scholarly articles, including over 13,000 with full text, about COVID-19 and the coronavirus family of viruses for use by the global research community. This dataset is intended to mobilize researchers to apply recent advances in natural language processing to generate new insights in support of the fight against this infectious disease. The corpus will be updated weekly as new research is published in peer-reviewed publications and archival services like bioRxiv, medRxiv, and others.

Live automated evidence via PubMed/ Clinical Trials/ F1000/ BioMedCentral/ bioRxiv/ medRxiv

In this 30-minute webinar, Dr. Veenema discusses disaster preparedness for nurses and nursing students in the event of an infectious disease outbreak with an emphasis on the current coronavirus (COVID-19) public health emergency.

Clinicians will learn what they can do to prepare for COVID-19 including identifying persons under investigation, applying infection prevention and control measures, assessing risks for exposures, optimizing the use of personal protective equipment supplies, and managing and caring for patients (inpatient and at home).

FREE. In this 30-minute webinar, Paul Auwaerter MBA, MD, Professor of Medicine at Johns Hopkins University, will deliver a full understanding of COVID-19 and how utilizing updated, authoritative, and evidence-based resources, such as the Johns Hopkins ABX Guide, can play a key role in your patient care.

In this audio interview conducted on March 10, 2020, the editors discuss the care of two hypothetical patients who present with equivocal symptoms.

What is COVID-19 and how might the outbreak affect you? Find out more about coronavirus and explore its worldwide implications.
Duration: 3 weeks Weekly study: 4 hours Learn: Free Digital upgrade: Free

COVID-19 news is changing rapidly and we are all trying to stay on top of the latest medical information from trusted sources. Join Dr. Paul Auwaerter from Johns Hopkins School of Medicine and the former president of the Infectious Diseases Society of America for a free CME webinar covering what we know about the coronavirus outbreak. Earn up to 1.0 CME/CE credits for participation.

SCCM's Critical Care for the Non-ICU Clinician provides online education to healthcare professionals who may benefit from critical care training. Be prepared with this free resource.

his course provides a general introduction to COVID-19 and emerging respiratory viruses and is intended for public health professionals, incident managers and personnel working for the United Nations, international organizations and NGOs.

This free Teach-Out is for anyone who has been curious about how we identify and measure outbreaks like the COVID-19 epidemic and wants to understand the epidemiology of these infections.

Hear expert advice on using outdated or expired masks, how to get multiple uses from masks, cleaning and disinfection procedures, UV disinfection, navigating supply-chain shortages, and why ECRI does not recommend homemade masks for healthcare facilities. The presentation concludes with an informative Q&A session based on questions from hospitals around the globe.

Best Practice Resources, What Nurses Need to Know, Information for Healthcare Consumers, Information for People Traveling, Volunteer Resources and Response, & Advocacy

To support the information needs of nursing school deans, faculty, students, and other stakeholders, AACN has developed this resource center to highlight key information sources about the Coronavirus Disease 2019 (COVID-19) found on the web.

Patients with confirmed or possible SARS-CoV-2 infection should wear a facemask when being evaluated medically.

Healthcare personnel should adhere to Standard, Contact, and Airborne Precautions, including the use of eye protection (e.g., goggles or a face shield) when caring for patients with SARS-CoV-2 infection. These precautions include the use of PPE, including NIOSH-approved N95 respirators, gowns, gloves, face shield/eye protection, etc. This includes, but is not limited to, surgical N95 respirators.

Strategies for Optimizing the Supply of N95 Respirators offers a series of strategies or options on how healthcare facilities can optimize supplies of disposable N95 filtering facepiece respirators when there is limited supply availability. This checklist is intended to help healthcare facilities prioritize the implementation of the strategies following the prioritization used in the concept of surge capacity. The strategies are categorized in a continuum of care and further organized according to the hierarchy of controls.

Best matches for the three most popular exam gloves, disinfecting wipes, isolation gowns, IV solutions, N95 air purifying respirators, shoe covers, and surgical masks, based on key performance indicators (KPIs) and functional equivalence. Proprietary database includes manufacturer name, catalog number, percentage match, median price, and KPI details.

Extended Use and Limited Reuse of Disposable Facemasks, Respirators and Protective Eyewear

Data/Specs for Manufacturers/Home Makers

The decision to discontinue Transmission-Based Precautions for hospitalized patients with COVID-19 should be made on a case-by-case basis in consultation with clinicians, infection prevention and control specialists, and public health officials. This decision should consider disease severity, illness signs and symptoms, and results of laboratory testing for COVID-19 in respiratory specimens. Guidance for discontinuation of in-home isolation precautions is the same as that to discontinue Transmission-Based Precautions for hospitalized patients with COVID-19. Considerations to discontinue Transmission-Based Precautions include all of the following:

• Resolution of fever, without use of antipyretic medication
  
• Improvement in illness signs and symptoms
  
• Negative results of an FDA Emergency Use Authorized molecular assay for COVID-19 from at least two consecutive sets of paired nasopharyngeal and throat swabs specimens collected ≥24 hours apart* (total of four negative specimens—two nasopharyngeal and two throat). See Interim Guidelines for Collecting, Handling, and Testing Clinical Specimens from Patients Under Investigation (PUIs) for 2019 Novel Coronavirus (2019-nCoV) for specimen collection guidance.
  

Patients can be discharged from the healthcare facility whenever clinically indicated. Isolation should be maintained at home if the patient returns home before the decision is made to discontinue Transmission-Based Precautions. The decision to send the patient home should be made in consultation with the patient’s clinical care team and local or state public health departments and should include considerations of the home’s suitability for and patient’s ability to adhere to home isolation recommendations, and potential risk of secondary transmission to household members with immunocompromising conditions.

See:

• CDC Interim Guidance for Home Care of patients with confirmed COVID-19 and persons under investigation for COVID-19.
• Interim Guidance for Preventing 2019-nCoV from Spreading to Others in Homes and Communities
• Interim Guidance for Discontinuation of In-Home Isolation for Patients with COVID-19.

If PSAP call takers advise that the patient is suspected of having COVID-19, EMS clinicians should put on appropriate PPE before entering the scene. EMS clinicians should consider the signs, symptoms, and risk factors of COVID-19.

If information about potential for COVID-19 has not been provided by the PSAP, EMS clinicians should exercise appropriate precautions when responding to any patient with signs or symptoms of a respiratory infection. Initial assessment should begin from a distance of at least 6 feet from the patient, if possible. Patient contact should be minimized to the extent possible until a facemask is on the patient. If COVID-19 is suspected, all PPE as described below should be used. If COVID-19 is not suspected, EMS clinicians should follow standard procedures and use appropriate PPE for evaluating a patient with a potential respiratory infection.

If a pregnant patient who has confirmed COVID-19 or is a PUI is arriving via transport by emergency medical services, the driver should contact the receiving emergency department or healthcare facility and follow previously agreed-upon local or regional transport protocols.

SCCM's Critical Care for the Non-ICU Clinician provides online education to healthcare professionals who may benefit from critical care training. Be prepared with this free resource.

This Special Collection includes Cochrane Reviews on the following topics: fluid and vasopressor therapy; respiratory support and mechanical ventilation; weaning mechanical ventilation; managing hypoxaemia; pharmacological treatment; and nutrition in intensive care. Many reviews in the collection have associated Cochrane Clinical Answers, with links provided.

It is important to note that the reviews included in this Collection summarise evidence; their inclusion does not mean that they are an effective treatment. A number of reviews presented here highlight the paucity of high-quality evidence to inform medical decision-making in the context of the severe acute respiratory infection (SARI) crisis.

The true impact of a COVID-19 outbreak in a U.S. community cannot be predicted. However, all healthcare facilities can take steps now to prepare for such an outbreak and protect both their patients and staff.

Clinicians will learn what they can do to prepare for COVID-19 including identifying persons under investigation, applying infection prevention and control measures, assessing risks for exposures, optimizing the use of personal protective equipment supplies, and managing and caring for patients (inpatient and at home).

Although it is not possible to predict the future course of the outbreak, planning for a scenario in which many persons become ill and seek care at the same time is an important part of preparedness and can improve outcomes if an outbreak occurs. Therefore, preserving healthcare system functioning is paramount. It is critical for healthcare facilities to continue to provide care for all patients, irrespective of COVID-19 infection status, at the appropriate level (e.g., home-based care, outpatient, urgent care, emergency room, or hospitalization).

Although it is not possible to predict the future course of the outbreak, planning for a scenario in which many persons become ill and seek care at the same time is an important part of preparedness and can improve outcomes if an outbreak occurs. Therefore, preserving healthcare system functioning is paramount. It is critical for healthcare facilities to continue to provide care for all patients, irrespective of COVID-19 infection status, at the appropriate level (e.g., home-based care, outpatient, urgent care, emergency room, or hospitalization).

This video on COVID-19 Emergency Preparedness Planning from CHC's Weitzman Institute focuses on the role of FQHC leadership, staff support, and key strategies for preparedness and easing anxiety.

A curated list of PubMed articles relevant to COVID-19 in dentistry. Updated daily

The true impact of a COVID-19 outbreak in a U.S. community cannot be predicted. However, all healthcare facilities can take steps now to prepare for such an outbreak and protect both their patients and staff.

Although it is not possible to predict the future course of the outbreak, planning for a scenario in which many persons become ill and seek care at the same time is an important part of preparedness and can improve outcomes if an outbreak occurs. Therefore, preserving healthcare system functioning is paramount. It is critical for healthcare facilities to continue to provide care for all patients, irrespective of COVID-19 infection status, at the appropriate level (e.g., home-based care, outpatient, urgent care, emergency room, or hospitalization).

Infection control procedures including administrative rules and engineering controls, environmental hygiene, correct work practices, and appropriate use of personal protective equipment (PPE) are all necessary to prevent infections from spreading during healthcare delivery. Prompt detection and effective triage and isolation of potentially infectious patients are essential to prevent unnecessary exposures among patients, healthcare personnel, and visitors at the facility. All healthcare facilities must ensure that their personnel are correctly trained and capable of implementing infection control procedures; individual healthcare personnel should ensure they understand and can adhere to infection control requirements.

This video on COVID-19 Emergency Preparedness Planning from CHC's Weitzman Institute focuses on the role of FQHC leadership, staff support, and key strategies for preparedness and easing anxiety.

The true impact of a COVID-19 outbreak in a U.S. community cannot be predicted. However, all healthcare facilities can take steps now to prepare for such an outbreak and protect both their patients and staff.

Clinicians will learn what they can do to prepare for COVID-19 including identifying persons under investigation, applying infection prevention and control measures, assessing risks for exposures, optimizing the use of personal protective equipment supplies, and managing and caring for patients (inpatient and at home).

Long-term care facilities concerned that a resident, visitor, or employee may be a COVID-2019 patient under investigation should contact their local or state health department immediately for consultation and guidance.

The general strategies CDC recommends to prevent the spread of COVID-19 in LTCF are the same strategies these facilities use every day to detect and prevent the spread of other respiratory viruses like influenza.

Although it is not possible to predict the future course of the outbreak, planning for a scenario in which many persons become ill and seek care at the same time is an important part of preparedness and can improve outcomes if an outbreak occurs. Therefore, preserving healthcare system functioning is paramount. It is critical for healthcare facilities to continue to provide care for all patients, irrespective of COVID-19 infection status, at the appropriate level (e.g., home-based care, outpatient, urgent care, emergency room, or hospitalization).

Since maternity and newborn care units vary in physical configuration, each facility should consider their appropriate space and staffing needs to prevent transmission of the virus that causes COVID-19. These considerations include appropriate isolation of pregnant patients who have confirmed COVID-19 or are PUIs; basic and refresher training for all healthcare personnel on those units to include correct adherence to infection control practices and personal protective equipment (PPE) use and handling; sufficient and appropriate PPE supplies positioned at all points of care; and processes to protect newborns from risk of COVID-19.

Refer to this information when managing pediatric patients with confirmed or suspected COVID-19.

As the COVID-19 pandemic evolves, the AAP has been staying abreast of all confirmed developments related to its global spread and will continue to be vigilant in efforts to develop and share information and guidance with members

Utilizing preparedness principles to mobilize pediatricians to adapt protocols, learn new models, and serve as champions for children in a pandemic.

COVID-19 Fact Sheets available in 34 languages. All materials are reviewed and vetted by physicians and medical school faculty members at the Harvard hospitals, created in collaboration with Harvard Health Publishing.

Helping clinicians understand how to talk to and support children during the COVID-19 pandemic, including how to help parents talk to their children.

A constantly updated page on the novel coronavirus that covers both the science and practical guidance for parents, including a new resource on social distancing. Also offers new tips for helping parents find ways to occupy children during these challenging times.